Pathogenic Mechanisms
The great majority of tubulointerstitial disorders occur as a result of one of three general mechanisms: heredity, toxic injury, or a change in tubule regulation by drugs or hormones. Polycystic kidney disease, familial nephrogenic diabetes insipidus, and Fanconi’s syndrome are disorders of hereditary origin. The specific genetic defects are unknown. Analgesic nephropathy, lead nephropathy, and some types of renal tubular acidosis are representative of toxic injuries. Pituitary diabetes insipidus (ADH deficiency), adrenal salt wasting (deficient mineralocorticoid), and diuretic administration are examples of the last category .
- MEDICAL MANAGEMENT OF ANGINA
- EFFECTS OF PULMONARY HYPERTENSION ON PULMONARY FUNCTION
- PERIPHERAL VENOUS DISEASE
- SPECIFIC PATHOGENIC ORGANISMS
- Treatment and Prognosis
- Direct (Toxic Nephropathy)
- BRORICHODILATORS
- TREATMENT
- Treatment
- GLOMERULAR DISEASE
- ELECTRICAL CONDUCTION SYSTEM
- Familial Polyposis of the Colon
- CLASSIFICATION AND PATHOPHYSIOLOGY
- COMMON PRESENTING COMPLAINTS
- Proteinuria
- NONRESPIRATORY FUNCTIONS OF THE LUNG
- Focal Glomerular Sclerosis (FQS)
- Comprehensive Health-care Program for Children in Foster Care
- MYOCARDIAL METABOLISM
- Sodium Retention
- ATHEROSCLEROSIS
- Renal Glycosuria
- PHYSICAL EXAMINATION
- Chromic Renal Failure Due to Drugs
- SCREENING TESTS OF HEPATOBILIARY DISEASE
- Renal Tumors
- HEMODIALYSIS AND HEMOPERFUSION IN THE TREATMENT OF DRUG OVERDOSES
- Etiology and Pathogenesis
- Complications of Dialysis
- Lower GI Bleeding
- Idiopathic Pulmonary Fibrosis
- NORMAL GASTRIC PHYSIOLOGY
- THE BLOOD VESSELS STRUCTURE
- OBLITERATIVE OR OBSTRUCTIVE PULMONARY HYPERTENSION
- SPECIFIC ENTITIES - DISEASES WITH KFiOWIi ETIOLOGIES -